928797.Ĭomparison of baseline data ( n (%)). This study has been reviewed and approved by the Medical Ethics Committee of the Qingdao Hospital of Traditional Chinese Medicine, No. The baseline characteristics of the routine group (22 males, 18 females, mean age of 57.67 ± 3.48 years, mean disease duration of 14.21 ± 2.25 years, and mean dialysis time of 12.66 ± 3.59 months) were comparable with those of the primary group (23 males, 17 females, mean age of 57.28 ± 3.56 years, mean disease duration of 14.13 ± 2.31 years, and mean dialysis time of 12.87 ± 3.45 months) ( ) (Table 1). Baseline Dataīetween July 2019 and April 2021, 80 patients with diabetic nephropathy who underwent hemodialysis in our institution were recruited and assigned at a ratio of 1 : 1 to either a routine group or a primary group. In the present study, 80 patients with diabetic nephropathy undergoing hemodialysis in our institution were recruited to assess the clinical effects of primary nursing on these patients and its impact on inflammatory responses. Although primary nursing care modality has been applied in numerous departments and diseases, the reports on diabetic nephropathy undergoing hemodialysis remain scant. A large body of clinical research has demonstrated the importance of active and effective nursing measures for diabetic nephropathy patients undergoing hemodialysis. Hemodialysis can effectively improve the life quality of patients with diabetic nephropathy with a high safety profile however, patients after hemodialysis treatment are predisposed to various complications, which seriously impair their physiological and psychological health and even threaten their life safety in serious cases. Diabetic nephropathy seriously compromises the life quality of patients. The loss of metabolic function of the kidney over a certain level will progress to uremia, which requires dialysis treatment or kidney transplantation. Chronic hyperglycemia in patients leads to sustained damage to the renal vasculature due to blood pressure, which results in blood filtration overload in the kidneys and thus nephropathy. The main cause of diabetic nephropathy is the untimely and ineffective control of diabetes. Diabetic nephropathy is one of the common comorbidities of diabetes mellitus, and its incidence has also been increasing. In recent years, with improvements in people’s living standards, the incidence of diabetes mellitus has been on the rise. Primary nursing improves the renal function of diabetic nephropathy patients undergoing hemodialysis, reduces the inflammatory response, and eliminates their negative emotions, which shows great potential for clinical application. The patients in the primary group had significantly lower scores on the self-rating anxiety scale (SAS) and self-rating depression scale (SDS) versus those in the routine group ( ). Patients receiving primary nursing showed significantly lower levels of interleukin (IL)-6, high-sensitivity C-reactive protein (hs-CRP), and tumor necrosis factor-alpha (TNF- α) versus those given routine nursing ( ).
Primary nursing resulted in lower levels of blood creatinine, fasting glucose, urea nitrogen, and proteinuria versus routine nursing ( ). The outcome measures included nursing outcomes, inflammatory factor levels, and psychological status.
Between July 2019 and April 2021, 80 patients with diabetic nephropathy who underwent hemodialysis in our institution were recruited and assigned at a ratio of 1 : 1 to receive either routine nursing (routine group) or primary nursing (primary group).
To assess the clinical effects of primary nursing on diabetic nephropathy patients undergoing hemodialysis and its impact on inflammatory responses.